Author's reply

BMJ 1996; 313 doi: https://doi.org/10.1136/bmj.313.7060.815b (Published 28 September 1996) Cite this as: BMJ 1996;313:815
  1. David P Strachan, Reader in epidemiology
  1. St George's Hospital Medical School, London SW17 0RE

    EDITOR,—Kim Hinshaw asks whether the beneficial association between bleeding during pregnancy and asthma relates to bleeding in the first or second trimester. Unfortunately, the information from the 1958 perinatal morbidity survey does not distinguish between bleeding in the first trimester and bleeding at other times.

    My colleagues and I are aware that false positive results may emerge from multiple comparisons, as Rollo Clifford points out, and we therefore stated that the associations with maternal albuminuria and antenatal haemorrhage were unexpected and “deserve further investigation.” Until …

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