Neurological effects of organophosphate pesticides

BMJ 1996; 313 doi: https://doi.org/10.1136/bmj.313.7058.690c (Published 14 September 1996) Cite this as: BMJ 1996;313:690
  1. Fidias E Leon-S, Clinical fellow,
  2. Gustavo Pradilla, Chief,
  3. Esperanza Vesga, Chief
  1. Department of Neurology, University of Alabama, Birmingham, AL 35294, USA
  2. Unit of Neurology, Department of Internal Medicine, UIS-Santander University School of Medicine, Bucaramanga, Colombia
  3. Unit of Toxicology, Department of Basic Sciences, UIS-Santander University School of Medicine, Bucaramanga, Colombia

    EDITOR,—Intoxication with organophosphates may produce acute and delayed neurotoxicity in humans as well as the chronic neurological effects recently described by Kyle Steenland.1 However, Steenland did not discuss the intermediate neurotoxic syndrome, which usually develops 24 to 96 hours after ingestion and is characterised by cranial nerve palsies, neck and proximal limb weakness, and respiratory paralysis.2 We recently reported that this syndrome could also be due to carbamate intoxication.3 It is unresponsive to …

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