Authors' reply

BMJ 1996; 313 doi: 10.1136/bmj.313.7055.490b (Published 24 August 1996)
Cite this as: BMJ 1996;313:490.3

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  1. Michael Barza, Professor of medicine,
  2. John Ioannidis, Research fellow,
  3. Joseph Lau, Associate professor
  1. New England Medical Center Hospitals, Tufts University School of Medicine, Boston, MA 02111, USA

    EDITOR,—Harry Campbell asks for an interpretation of the findings of our meta-analysis in young children, particularly neonates. None of the data we found apply specifically to the neonatal period, although there are some data for older infants. Marik et al studied 132 patients under 1 year of age, the mean (SD) age being 0.35 (0.26) years in the group given once daily doses and 0.41 (0.31) years in the group given twice daily doses.1 The authors do …

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