Tea flavonoids have little short term impact on serum antioxidant activity

doi:10.1136/bmj.313.7051.229a

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Simon Maxwell,
Gary Thorpe

Senior lecturer Division of Clinical Pharmacology, Leicester Royal Infirmary, Leicester LE2 7LX
Biochemical director Wolfson Applied Technology Laboratory, Queen Elizabeth Hospital, Birmingham B15 2TH

EDITOR,—There is currently much interest in the possible benefits of dietary flavonoids in preventing cardiovascular diseases.1 2 The apparent protective effect has been attributed to the potent antioxidant activity of flavonoids. In vitro flavonoids are powerful inhibitors of the oxidation of low density lipoproteins, a process that has been strongly implicated in the development of atherosclerosis.3 For some years we have been using enhanced chemiluminescence as a simple method of measuring antioxidant activity in biological …