Letters

Costs and getting ethical approval deter doctors from participating in multicentre trials

BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7047.1669a (Published 29 June 1996) Cite this as: BMJ 1996;312:1669
  1. S W Crooks,
  2. S B Colman,
  3. I A Campbell
  1. Research registrar Department of Respiratory Medicine, Queen Elizabeth Hospital Medical Centre, Birmingham B15 2TH
  2. Course organiser, department of therapeutics and clinical pharmacology Consultant in thoracic medicine University of Wales College of Medicine, Llandough Hospital, Cardiff CF64 2XX

    EDITOR,—Many questions in medicine can be answered only if large numbers of patients are studied, and multicentre trials are normally necessary for this. The research committee of the British Thoracic Society, which has conducted many multicentre trials,1 designed two studies on the prevention and treatment of osteoporosis by hormone replacement therapy and/or etidronate and/or calcium in asthmatic patients taking cor-ticosteroids. Height, weight, activity status, fractures, and (if available) results of bone densitometry were recorded annually for five years. Lateral radiographs of the thoracolumbar spine were obtained at …

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