Reply from author of review

doi:10.1136/bmj.312.7046.1611

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John R Absher

Assistant professor of neurology Bowman Gray School of Medicine, Winston-Salem, North Carolina, USA

EDITOR,—Jammi N Rao and J D Middleton mention “deficiencies” of my review in Evidence-Based Medicine of the trial of interferon beta-1b. They raise two basic points that deserve a response. Firstly, they caution that my review was not “sufficiently critical of the evidence” and support this claim by noting the “almost diametrically opposite conclusions” reached by me and an anonymous reviewer. Secondly, they criticise “the approach taken by Evidence-Based Medicine” and “warn” readers who rely …