Concerns about chemotherapy are legitimate

BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7043.1417a (Published 01 June 1996) Cite this as: BMJ 1996;312:1417
  1. Richard Gray,
  2. John Northover
  1. ICRF senior research fellow Clinical Trial Service Unit, Radcliffe Infirmary, Oxford OX2 6HE
  2. Honorary director ICRF Colorectal Cancer Unit, St Mark's Hospital, Harrow, Middlesex HA1 3UJ

    EDITOR,—Maurice L Slevin's editorial on adjuvant treatment in colorectal cancer reflects the prevailing conviction among oncologists about the beneficial effect of chemotherapy on survival in this disease.1 Unfortunately, Slevin probably overestimates the real effect because he selectively emphasises particular trials that have reported a survival benefit while ignoring other studies, testing identical regimens, in which no benefit was apparent (N Wilking, Stockholm colorectal cancer symposium, Stockholm, 12-13 Oct 1995).2 3 Moreover, even in those trials cited, the reported improvements in survival are …

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