Letters

Is there evidence to show that daily antibiotic treatment is best?

BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7042.1360d (Published 25 May 1996) Cite this as: BMJ 1996;312:1360
  1. Chris Butler,
  2. Paul Kinnersley
  1. Lecturer in general practice Senior lecturer in general practice University of Wales College of Medicine, Llanedeyrn Health Centre, Cardiff CF3 7PN

    EDITOR,—The recent guidelines on preventing and managing infection in patients with an absent or dysfunctional spleen recommend lifelong prophylaxis with oral antibiotics for all patients who have undergone splenectomy.1 People who receive this advice may ask about their baseline risk of dangerous sepsis, how this will be reduced by taking medicine every day, and other options for prevention.

    The risk of serious …

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