US doctors warned about test for breast cancer geneBMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7038.1057b (Published 27 April 1996) Cite this as: BMJ 1996;312:1057
A test that is purported to identify women at high risk of breast cancer is at the centre of a growing debate in the US among researchers, regulators, private laboratories, and women. The test is a genetic analysis to detect mutations of the BRCA1 gene, which lies on chromosome 17.
The mutation, which is more common in Ashkenazi Jewish women, is thought to confer an 80-90% lifetime risk …
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