Predictors of neonatal encephalopathy in full term infants

BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7030.580 (Published 02 March 1996) Cite this as: BMJ 1996;312:580

More information needed about possible role of thyroxine

  1. J Girling,
  2. M De Swiet
  1. Senior registrar in obstetrics and gynaecology Hammersmith Hospital, London W12 0HS
  2. Consultant physician Queen Charlotte's and Chelsea Hospital, London W6 0XG

    EDITOR,—Stuart J Adamson and colleagues suggest that maternal thyroxine treatment increases the risk of neonatal encephalopathy, with an odds ratio of between 1.2 and infinity (the mothers of six of the affected babies were taking thyroxine, compared with none of the mothers of the control babies).1 They also claim that this is biologically plausible. These statements need further qualification in view of …

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