Fortnightly Review: A rational approach to the management of hepatitis C infectionBMJ 1996; 312 doi: http://dx.doi.org/10.1136/bmj.312.7027.357 (Published 10 February 1996) Cite this as: BMJ 1996;312:357
- G M Dusheiko, reader in medicinea,
- S Khakoo, research fellowa,
- P Soni, South African MRC fellowa,
- L Grellier, British Digestive Foundation research fellowa
- Correspondence to: Dr Dusheiko.
The natural course of chronic hepatitis C is not fully defined
A range of disease exists—from mild asymptomatic infection with few consequences to serious disease with dire sequelae
Pretreatment assessments of viral load and genotype or serotype may help in predicting response
It is difficult to indicate the prognosis for younger patients with mild disease; they may need to be considered for treatment, so that the opportunity to avoid later disease is not forfeited
It is not yet clear whether patients who are more responsive to interferon have a better prognosis
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