Editor's choiceBMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7027.0 (Published 10 February 1996) Cite this as: BMJ 1996;312:0
Lessons in pharmacology
Although trials of drug treatments often simply look at whether they work or not, this week's BMJ contains several papers that remind us that there are many other complexities to drug treatment.
One problem is to know who to treat. Hepatitis C infection, for example, may be benign, or it may lead to progressive disease and death. Some patients respond to interferon alfa, but some do not. A group from London offer a strategy for deciding who to treat based on testing viral load and genotyping and serotyping (p 357).
A second problem is …