Letters

How to get patients' consent to enter clinical trials

BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7024.185c (Published 20 January 1996) Cite this as: BMJ 1996;312:185

Reports of trials should state proportion of people who refuse to participate

  1. F Andrew I Riordan,
  2. Alistair P J Thomson
  1. Lecturer in paediatrics and child health Undergraduate Teaching Centre, Birmingham Heartlands Hospital, Birmingham B9 5SS
  2. Consultant paediatrician Leighton Hospital, Crewe, Cheshire CW1 4QJ

    EDITOR,—We agree with Elizabeth Wager and colleagues that “large proportions of patients refusing to enter studies may signal a problem with study design.1 The proportion of refusals, however, may vary with the nature of the trial, the disease studied, and the type of treatment investigated.

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