Aetiology of scrapie in certain circumstances is not evidence against another aetiology in different circumstances

doi:10.1136/bmj.312.7024.180a

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R M Ridley,
H F Baker

Head, MRC comparative cognition team Senior scientific officer Department of Experimental Psychology, Cambridge University, Cambridge CB2 3EB

EDITOR,—We are pleased that, in the commentary on our article on the myth of maternal transmission of spongiform encephalopathy, R G Will agrees that maternal transmission does not occur in human or experimental forms of spongiform encephalopathy and that the only circumstance in which it requires serious consideration is natural scrapie.1

The genetics of natural scrapie and the genetics of susceptibility to experimental transmission of scrapie in sheep differ. The characteristics and quantity of the agent, the …