Education And Debate

Epidemiological evidence concerning a possible causal link

BMJ 1995; 311 doi: https://doi.org/10.1136/bmj.311.7017.1418 (Published 25 November 1995) Cite this as: BMJ 1995;311:1418
  1. Albert Hofman, professor of epidemiologya,
  2. Dorothee P W M Wientjens, research physiciana
  1. aDepartment of Epidemiology and Biostatistics, Erasmus University Medical School, PO Box 1738, 3000 DR Rotterdam, Netherlands

    The occurrence of Creutzfeldt-Jakob disease in British dairy farmers possibly exposed to cattle with bovine spongiform encephalopathy has focused attention on the possibility of a causal link between the two diseases. We briefly review the currently available epidemiological evidence.

    The table shows the incidence of Creutzfeldt-Jakob disease in France, Germany, Italy, the Netherlands, and Britain. The data are based on registries in the countries, which have used similar methods of surveillance and criteria for diagnosis since the start of a European collaborative study in …

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