Drug Points

Exacerbation of idiopathic Parkinson's disease by naproxen

BMJ 1995; 311 doi: https://doi.org/10.1136/bmj.311.7002.422b (Published 12 August 1995) Cite this as: BMJ 1995;311:422
  1. S Shaunak,
  2. P S Brown,
  3. J A Morgan-Hughes

    Drs S SHAUNAK, P BROWN, and J A MORGAN-HUGHES (National Hospital for Neurology and Neurosurgery, London WC1N 3BG) write: A 74 year old woman with a 10 year history of idiopathic Parkinson's disease was prescribed naproxen 250 mg three times a day for musculoskeletal pain. Her symptoms had previously been well controlled with co-beneldopa (levodopa and benserazide hydrochloride) 375 mg a day, selegiline 10 mg a day, and propranolol 60 mg a day. Shortly after starting naproxen treatment she became immobile …

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