Drug Points

Interaction between cyclosporin and fluoxetine

BMJ 1995; 311 doi: https://doi.org/10.1136/bmj.311.7002.422 (Published 12 August 1995) Cite this as: BMJ 1995;311:422
  1. R C Horton,
  2. R S Bonser

    Dr R C HORTON and Mr R S BONSER (Queen Elizabeth Hospital, Birmingham B15 2TH) write: We report an interaction between cyclosporin and fluoxetine causing a rise in cyclosporin concentrations.

    A 59 year old man underwent cardiac transplantation for end stage heart failure. Cyclosporin was given as an immunosuppressant, and he was maintained on 225 mg twice daily with a stable trough whole blood concentration …

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