Minerva

Minerva

BMJ 1995; 311 doi: http://dx.doi.org/10.1136/bmj.311.7000.340 (Published 29 July 1995) Cite this as: BMJ 1995;311:340

A thought provoking new explanation for restenosis after coronary angioplasty is that the cause is proliferation of the vascular endothelium secondary to inhibition of the p53 gene by reactivation of cytomegalovirus infection (British Heart Journal 1995;73:489). Draw a deep breath: for clinicians the message is that antiviral treatment may possibly reduce the risk of restenosis. Experiments on animals have given some encouraging results.

Each year around nine children in the United States develop paralytic poliomyelitis from the oral vaccine in current use. The last case of wild polio occurred in 1979. Nevertheless, says a report in “JAMA,” the Advisory Committee on Immunisation Practices has not yet agreed to switch to the use of an inactivated vaccine. One possibility under discussion is to use an inactivated vaccine for the first dose and oral live vaccine for the second and third doses.

Screening newborn babies for cystic fibrosis has been feasible for about 15 years, but paediatricians still disagree about the value of such testing. A report from the Netherlands (Thorax 1995;50:712-8) claims that the early treatment given to children detected by screening …

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