Letters

Events per person year

BMJ 1995; 310 doi: https://doi.org/10.1136/bmj.310.6992.1469a (Published 03 June 1995) Cite this as: BMJ 1995;310:1469

This article has a correction. Please see:

A decrease in multiple events may be missed

  1. John A Kanis,
  2. Eugene V McCloskey
  1. Professor in human metabolism and clinical biochemistry Senior clinical research fellow WHO Collaborating Centre for Metabolic Bone Diseases, Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, Sheffield S10 2RX

    EDITOR,—Jurgen Windeler and Stefan Lange describe the “new measure” invented in 1982 to describe osteoporotic fractures in the context of clinical trials—namely, the frequency of vertebral fracture.1 They suggest that the number of patients developing vertebral fractures is a more appropriate end point. In their review they neglect to mention that the problems with this approach are well recognised,2 3 though perhaps not universally applied. Nor is the fallacy ignored by some registration authorities, and in some countries the test agents to which …

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