BMJ 1995; 310 doi: https://doi.org/10.1136/bmj.310.6981.750 (Published 18 March 1995) Cite this as: BMJ 1995;310:750

Research on volunteers in New York has come up with further evidence that people who want to lose or gain weight have a hard task ahead. The volunteers deliberately gained or lost 10% of their resting weight; those who had lost weight were then found to have reduced their resting energy expenditure, while those who had gained weight had increased it (New England Journal of Medicine 1995;332:621-8). In other words, the body's adipostat tends to keep body weight constant by adjusting the body's metabolism. Evidence from other studies of weight loss suggests that even after four years the body will still be trying to return to its initial weight.

Follow up of 220 patients with Parkinson's disease recruited in the early 1970s showed that after 20 years 195 had died at an average age of 77.6 years. The average age at death of controls was 83.5 years. The report in the “Journal of Neurology, Neurosurgery, and Psychiatry” (1995;58:293-99) calculates that the all cause hazard ratio for cases compared with controls was 2.6, but treatment has improved since the start of the research and prospects may now be better.

Campylobacter jejuni is often to be found in unpasteurised cows' milk and is usually assumed to be a contaminant that enters the milk during milking. A …

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