Serum C4 concentration and risk of atherosclerosis

BMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6961.1087a (Published 22 October 1994) Cite this as: BMJ 1994;309:1087
  1. L A Moreno,
  2. A Sarria,
  3. A Lazaro,
  4. M Bueno,
  5. L Larrad
  1. Departamento de Pediatria, Hospital Clinico Universitario “Lozano Blesa,” Facultad de Medicina, Universidad de Zaragoza, 50009 Zaragoza, Spain Servicio de Inmunologia, Hospital Clinico Universitario “Lozano Blesa”.

    EDITOR, - Judit Kramer and colleagues report a high prevalence of the C4B*Q0 allotype in patients with myocardial infarction.1 Muscari et al showed a significant assocation between serum C4 concentrations and the presence of severe atherosclerosis.2 We have studied, in our paediatric lipid research clinic, 243 children aged 2.0 to 15.9 years. We determined serum C4 concentrations in 107 children from 79 families who were referred to our clinic from 1990 to 1992 because serum total …

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