Results of prescription event monitoring study of salmeterol

BMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6960.1018b (Published 15 October 1994) Cite this as: BMJ 1994;309:1018
  1. R D Mann
  1. Drug Safety Research Unit, Southampton SO13 1AA

    EDITOR, - The prescription event monitoring study of salmeterol1 is now complete and has shown the number of deaths due to asthma in patients treated with the drug to be lower than that predicted. Last year Castle et al reported on 16 787 patients treated with salmeterol for 16 weeks.2 In these patients 54 deaths from all causes occurred (0.32%), including 12 from asthma (0.07%). The prescription event monitoring study has identified 1022 deaths (6.6%) in our cohort of 15 407 patients treated with salmeterol and observed for …

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