Paternal treatment for sterility and neonatal neuroblastomaBMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6951.410 (Published 06 August 1994) Cite this as: BMJ 1994;309:410
- A J Sasco,
- P Lutz,
- M Pinget,
- F Becmeur,
- D Satge,
- A Born
- Unit of Analytical Epidemiology, International Agency for Research on Cancer, 69372 Lyons Cedex 08
- France Centre Hospitalier Universitaire de Strasbourg, France Centre Hospitalier de Tulle, France Centre Hospitalier de Sarreguemines, France.
EDITOR, - Robaire and Hales have discussed the possible effects of paternal exposure to chemicals before conception.1 We report a case of neuroblastoma diagnosed as stage IVS at birth (with manifestations in the skin and liver accompanied by lumboaortic adenopathy) in a male infant born in France whose father had been treated for sterility.
Metaiodobenzylguanidine scans yielded negative results, and N-myc oncogene was not amplified. The first two courses of chemotherapy with vincristine and cyclophosphamide according to the NB90 protocol of the French …