Letters

Paternal treatment for sterility and neonatal neuroblastoma

BMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6951.410 (Published 06 August 1994) Cite this as: BMJ 1994;309:410
  1. A J Sasco,
  2. P Lutz,
  3. M Pinget,
  4. F Becmeur,
  5. D Satge,
  6. A Born
  1. Unit of Analytical Epidemiology, International Agency for Research on Cancer, 69372 Lyons Cedex 08
  2. France Centre Hospitalier Universitaire de Strasbourg, France Centre Hospitalier de Tulle, France Centre Hospitalier de Sarreguemines, France.

    EDITOR, - Robaire and Hales have discussed the possible effects of paternal exposure to chemicals before conception.1 We report a case of neuroblastoma diagnosed as stage IVS at birth (with manifestations in the skin and liver accompanied by lumboaortic adenopathy) in a male infant born in France whose father had been treated for sterility.

    Metaiodobenzylguanidine scans yielded negative results, and N-myc oncogene was not amplified. The first two courses of chemotherapy with vincristine and cyclophosphamide according to the NB90 protocol of the French …

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