New Developments in the Therapy of Allergic Disorders and AsthmaBMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6950.348 (Published 30 July 1994) Cite this as: BMJ 1994;309:348
- J P R Hartley
Ed S Z Langer, M K Church, B B Vargaftig, S Nicosia Karger, pp 136 ISBN 3-8055-5748-8
It is more than 80 years since Dale and his colleagues described the actions of a substance called beta iminazolylethyl amine, and the role of histamine, as it was later called, is still debated in meetings on allergy and asthma. Histamine seems to be most important in rhinitis and urticaria - where H1 antihistamines are thus valuable in treatment - and much less important in asthma. Despite extensive, and continuing, research, H1 antihistamines have not been found to be helpful for most …
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