Letters

Immunodeficiency without HIV Clinical presentations vary

BMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6941.1436 (Published 28 May 1994) Cite this as: BMJ 1994;308:1436
  1. M A Monteil,
  2. D C Henderson,
  3. S Obaro
  1. Department of Immunology, Charing Cross and Westminster Medical School, London SW10 9NH
  2. Divisions of Medicine and Pathology, Rotherham General Hospital, Rotherham S60 2UD.

    EDITOR, - A McNulty and colleagues reported on seven HIV negative patients with CD4 T lymphocytopenia and clinical disease due to defective cell mediated immunity.1 These cases were found during a national survey in Australia in which 96 practitioners were contacted. We present information on five HIV negative patients (four adults and one child) seen in our department between 1991 and 1993 (table) who meet the criteria set by McNulty and colleagues; two of them also satisfy the Centers for Disease Control's criteria for CD4 T lymphocytopenia as defined by McNulty and colleagues. All patients had been referred to our department of immunology for evaluation of suspected immunodeficiency.

    View this table:

    Details of HIV negative patients with CD4 lymphocytopenia

    In contrast to the Australian group, our patients presented with a diverse range of clinical problems, from planar warts …

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