Genetic susceptibility to non-insulin dependent diabetesBMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6927.534a (Published 19 February 1994) Cite this as: BMJ 1994;308:534
- L Groop,
- G F Bottazzo
- Department of Endocrinology, University of Lund, Malmo General Hospital, S-214 01 Malmo, Sweden
- Department of Immunology, London Hospital Medical College, London E1 2AD.
EDITOR, - Eva Tuomilehto-Wolf and coworkers have presented the interesting hypothesis that genetic susceptibility to non-insulin dependent diabetes mellitus is located in the HLA region. Their conclusions are based on findings in 157 elderly Finnish men (age 70-89), in whom HLA haplotypes associated with insulin dependent diabetes could explain 98% of non-insulin dependent diabetes and 79% of impaired glucose tolerance. This association depended strongly …