Intrauterine growth and serum cholesterol Link may be spuriousBMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6927.532a (Published 19 February 1994) Cite this as: BMJ 1994;308:532
- M Mongelli,
- J Gardosi
- Perinatal Research and Monitoring Unit, Queen's Medical Centre, Nottingham NG7 2UH
- MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO9 4XY
- Department of Clinical Biochemistry, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 2QR.
EDITOR, - Studies of associations between birth variables and adult morbidity such as that by D J P Barker and colleagues are of epidemiological interest, but the results need to be interpreted with caution.1 Even within the limitations of 50 years old records the authors' main conclusion - that raised cholesterol concentrations in adult life are associated with impaired growth during late gestation - is difficult to accept on the basis of the data presented.
It is difficult to infer growth retardation from any single measurement such as …