Letters

Clusters of anophthalmia: No link with benomyl in Italy..

BMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6922.205b (Published 15 January 1994) Cite this as: BMJ 1994;308:205
  1. F Bianchi,
  2. A Calabro,
  3. E Calzolari,
  4. P P Mastroiacovo,
  5. G Petrelli,
  6. A Spagnolo,
  7. R Tenconi
  1. Istituto Fisiologia Clinica del CNR, Dipartimento Epidemiologia e Biostatistica, 56124 Pisa, Italy Clinica Pediatrica, Universita, Perugia, Italy Instituto Genetica Medica, Universita, Ferrara, Italy Clinica Pediatrica, Universita Cattolica, Rome, Italy Istituto Superiore di Sanita, Laboratorio Epidemiologia e Biostatistica, Rome, Italy Dipartimento Pediatria, Universita, Padua, Italy.

    EDITOR, - Since the Observer reported a possible link between apparent clusters of anophthalmia and microphthalmia in England and Wales and the pesticide benomyl,1 several articles have commented on possible strategies to manage public and media concern, the methodology to identify clusters, the difficulty in assessing disease clusters with unreliable data, and the weakness of retrospective studies.*RF 2-5* Analysis of cases routinely reported to the national congenital malformation …

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