...and other diseases

BMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6922.200c (Published 15 January 1994) Cite this as: BMJ 1994;308:200
  1. W M O'Neill
  1. Bristol Oncology Centre, Bristol BS2 8ED.

    EDITOR, - M F Bristow and D Kohen acknowledge that psychiatry is not the sole domain of the neuroleptic malignant syndrome.1 The syndrome has been described in patients with advanced cancer2 and AIDS.3 Malnutrition and severe debility may be precipitating factors in susceptible patients. Outside psychiatry the diagnosis may often be missed as three of the four standard diagnostic criteria (fever, autonomic instability, and altered consciousness) may be seen as evidence of advancing malignant or other disease. All of these factors will contribute to an underestimation of its true incidence.


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