Research Article

Pigs susceptible to energy metabolism in the fulminant hyperthermia stress syndrome.

Br Med J 1975; 3 doi: https://doi.org/10.1136/bmj.3.5980.411 (Published 16 August 1975) Cite this as: Br Med J 1975;3:411

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  1. C H Williams,
  2. C Houchins,
  3. M D Shanklin

    Abstract

    Pigs susceptible to the fulminant hyperthermia-stress syndrome spontaneously developed the hyperthermia syndrome. Basal metabolic rates 10-fold higher than normal were observed in these animals. The metabolic rate exceeded a 17-fold increase over normal with a total heat production of over 28.25 J (6;76 kcal) h-1 kg-1. Heat loss by radiation ceased early in the syndrome, possibly owing to intense peripheral vasoconstriction--a finding which suggests that in man vasodilators might have an important therapeutic role.