Rosette-forming T Lymphocytes and Cell-mediated Immunity in MalnutritionBr Med J 1974; 3 doi: https://doi.org/10.1136/bmj.3.5931.608 (Published 07 September 1974) Cite this as: Br Med J 1974;3:608
- R. K. Chandra
The frequency of rosette-forming thymus-dependent lymphocytes was reduced in the peripheral blood of malnourished infants and children. The reduced frequency parallelled the impairment of delayed hypersensitivity response to 2, 4-dinitrochlorobenzene and decreased DNA synthesis by lymphocytes challenged with phytohaemagglutinin. The abnormalities were reversed on nutritional improvement.