Linoleate and Fatty-acid Patterns of Serum Lipids in Multiple Sclerosis and Other DiseasesBr Med J 1974; 3 doi: https://doi.org/10.1136/bmj.3.5922.18 (Published 06 July 1974) Cite this as: Br Med J 1974;3:18
- W. Clayton Love,
- A. Cashell,
- M. Reynolds,
- Noel Callaghan
The linoleic acid content of serum lipids was measured in 47 patients with multiple sclerosis, 29 patients with other neurological diseases, 35 patients with acute non-neurological illnesses, and 49 healthy control subjects. Reduced linoleic acid content of serum lipids was not specific to multiple sclerosis and occurred in all ill patients with acute non-neurological illness. The fatty-acid pattern of serum lipids in illness resembles that of essential fatty-acid deficiency. It seems that this pattern of reduced linoleic acid content with increased oleic, palmitic, and palmitoleic acid content may be a general phenomenon in ill patients.