Significance of Hyperamylasaemia and Abdominal Pain in Diabetic KetoacidosisBr Med J 1973; 3 doi: https://doi.org/10.1136/bmj.3.5872.128 (Published 21 July 1973) Cite this as: Br Med J 1973;3:128
- A. H. Knight,
- D. N. Williams,
- G. Ellis,
- D. M. Goldberg
An analysis of 35 consecutive episodes of diabetic ketoacidosis confirmed the frequent high levels of serum amylase in this condition. Serum amylase was raised during 21 episodes (60%), and in six instances (17%) the peak level exceeded 1,000 Somogyi units per 100 ml. Hyperamylasaemia was more often found when the initial blood sugar exceeded 500 mg/100 ml, or when the onset of the episode had been relatively acute (less than 48 hours). There was no conclusive evidence in any patient to support a diagnosis of acute pancreatitis and other explanations for the hyperamylasaemia are discussed. Even grossly raised amylase levels were not associated with increased mortality or morbidity.