Papers And Originals

Screening for Malignant Hyperpyrexia

Br Med J 1972; 3 doi: (Published 02 September 1972) Cite this as: Br Med J 1972;3:559
  1. F. Richard Ellis,
  2. Niall P. Keaney,
  3. D. G. F. Harriman,
  4. D. W. Sumner,
  5. K. Kyei-Mensah,
  6. J. H. Tyrrell,
  7. J. B. Hargreaves,
  8. R. K. Parikh,
  9. P. L. Mulrooney


    The methods used to screen patients for malignant hyperpyrexia at present are not sufficiently accurate. This paper reports more specific methods of detecting patients liable to develop malignant hyperpyrexia. A motor-point muscle biopsy is performed for histopathological examination and to detect muscle contracture in vitro after exposure to halothane and suxamethonium.