Prostaglandin-like Activity in Ocular InflammationBr Med J 1972; 3 doi: https://doi.org/10.1136/bmj.3.5824.452 (Published 19 August 1972) Cite this as: Br Med J 1972;3:452
- K. E. Eakins,
- R. A. F. Whitelocke,
- A. Bennett,
- A. C. Martenet
Aqueous humour samples from untreated patients with acute anterior uveitis were found to contain substantial amounts of prostaglandin-like activity. Little activity was found in aqueous from patients treated with steroids, and none (<2 ng/ml) was detected in aqueous from the uninflamed eyes of patients with cataract. Alkaline hydrolysis of the samples from inflamed eyes suggested the presence of both E and F prostaglandin-like activity. These results show that prostaglandins may be involved in acute anterior uveitis.