Papers And Originals
Immunological Responses in Pregnancy and Survival of Fetal Homograft
Br Med J 1972; 3 doi: https://doi.org/10.1136/bmj.3.5819.150 (Published 15 July 1972) Cite this as: Br Med J 1972;3:150- Ronald Finn,
- C. A. St. Hill,
- A. Jane Govan,
- I. G. Ralfs,
- Frances J. Gurney,
- Vivien Denye
Abstract
Immunological responses were studied in pregnant women and controls using as tests phytohaemagglutinin-induced lymphocyte transformation and the tuberculin reaction. Significantly reduced responses were found to both tests in the pregnant women. These results suggest that a reduction in T-cell activity during pregnancy may help protect the fetus from rejection by its mother's immunological mechanisms.