Papers And Originals

Trimethoprim-sulphamethoxazole in Acute Brucellosis

Br Med J 1971; 3 doi: https://doi.org/10.1136/bmj.3.5767.159 (Published 17 July 1971) Cite this as: Br Med J 1971;3:159

This article has a correction. Please see:

  1. A. Hassan,
  2. M. M. Erian,
  3. Z. Farid,
  4. S. D. Hathout,
  5. K. Sorensen

    Abstract

    Eight patients with proved brucella infection were treated with trimethoprim-sulphamethoxazole. The dose varied from two to four tablets given twice daily for three weeks. Clinical response was rapid and all patients were asymptomatic and afebrile within two to seven days of starting therapy. Three patients relapsed clinically and bacteriologically within three weeks of ending treatment. There were no side effects of the treatment. It is suggested that the treatment be continued for at least six weeks to prevent relapses.