Papers And Originals

Changes in Gut Flora after Cephalexin Treatment

Br Med J 1970; 3 doi: https://doi.org/10.1136/bmj.3.5723.624 (Published 12 September 1970) Cite this as: Br Med J 1970;3:624
  1. H. Gaya,
  2. P. I. Adnitt,
  3. P. Turner

    Abstract

    Eighteen patients with urinary tract infection were treated with cephalexin orally. Absorption was variable, between 29 and 89% of the total daily dose being excreted in the urine in 24 hours. A significant number of patients became faecal carriers of Pseudomonas aeruginosa compared with a control group who received no antibiotics. Four of the cephalexin-treated patients acquired a strain of Ps. aeruginosa known to be present in food from the hospital diet kitchen and one developed a urinary tract infection with this strain.