Fibrin Degradation Products in Pre-eclamptic Toxaemia and EclampsiaBr Med J 1970; 3 doi: http://dx.doi.org/10.1136/bmj.3.5722.545 (Published 05 September 1970) Cite this as: Br Med J 1970;3:545
- A. H. Henderson,
- D. J. Pugsley,
- D. P. Thomas
Serum levels of fibrinogen/fibrin degradation products, measured in African women, were significantly higher in pre-eclamptic toxaemia than in normal pregnancy, and were significantly higher with eclampsia than with toxaemia. These findings are in accord with the hypothesis that eclampsia and toxaemia are associated with disseminated intravascular coagulation, which may be responsible for certain clinical manifestations of these conditions.