Glycolytic Enzymes in Adipose Tissue of Adult DiabeticsBr Med J 1970; 3 doi: https://doi.org/10.1136/bmj.3.5720.444 (Published 22 August 1970) Cite this as: Br Med J 1970;3:444
- D. J. Galton,
- J. P. D. Wilson
The maximal activities of hexokinase and phosphofructokinase were measured in human adipose tissue. Though the mean activity of hexokinase was similar between a group of adult diabetics (n=24) and a group of non-diabetic controls (n=25), in the diabetic group the activity of phosphofructokinase was definitely reduced. Possibly this enzyme deficiency might contribute to impaired glucose utilization by the adipose cell in diabetes.
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