Preliminary Communications

Simple Method for Determining Isoniazid Acetylator Phenotype

Br Med J 1970; 3 doi: (Published 08 August 1970) Cite this as: Br Med J 1970;3:324
  1. D. W. Russell


    Methods have been developed for estimating acetylisoniazid and isoniazid in urine without a spectrophotometer. In experiments with volunteers the ratio of acetylisoniazid to isoniazid in urine samples collected the morning after three spaced oral doses each of 100 mg. was bimodally distributed.

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