Preliminary Communications

Potentiation of Insulin Action in Normal Subjects by a Pituitary Polypeptide

Br Med J 1969; 3 doi: (Published 23 August 1969) Cite this as: Br Med J 1969;3:451
  1. J. Bornstein,
  2. J. McD. Armstrong,
  3. F. M. Ng,
  4. H. P. Taft


    A pituitary polypeptide, acceleratory polypeptide-growth hormone (ACG), has been found to increase the sensitivity of fasting normal people to intravenous insulin. It is suggested that diminished activity of this polypeptide—or increased activity of another polypeptide, inhibitory polypeptide-growth hormone (ING)—may have a role in the genesis of diabetes mellitus.

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