Papers And Originals

Effects of β-Adrenergic Receptor Blockade on Airway Conductance and Lung Volume in Normal and Asthmatic Subjects

Br Med J 1969; 3 doi: http://dx.doi.org/10.1136/bmj.3.5663.143 (Published 19 July 1969) Cite this as: Br Med J 1969;3:143
  1. P. S. Richardson,
  2. G. M. Sterling

    Abstract

    Ten normal and five asthmatic subjects were given intravenous injections of 10 ml. of 0·9% saline with and without 10 mg. of propranolol, and specific airway conductance was followed in a whole-body plethysmograph. Saline alone had no significant effect on conducatance in either group of subjects. Propranolol had no significant effect on conductance in normal subjects, but caused a mean fall of 34·9% in the asthmatics.