Reversal of Folate Malabsorption in Tropical and Non-tropical Sprue by Calf JejunumBr Med J 1968; 3 doi: https://doi.org/10.1136/bmj.3.5616.472 (Published 24 August 1968) Cite this as: Br Med J 1968;3:472
- H. Baker,
- O. Frank,
- H. Ziffer,
- S. Feingold,
- A. A. Cintron-Rivera
In eight patients with folic acid malabsorption the malabsorption was reversed only when a combination of either 250 mg. of lyophilized human jejunal juice or 5 g. of lyophilized calf jejunum with 5 mg. of synthetic folic acid was fed; calf liver was ineffective. The factors in calf jejunum that re-established folic acid absorption were heat-stable and did not form polyglutamyl folates on previous incubation with folic acid.
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