Preliminary Communications

Rubidomycin in Acute Leukaemia in Adults

Br Med J 1968; 3 doi: https://doi.org/10.1136/bmj.3.5612.227 (Published 27 July 1968) Cite this as: Br Med J 1968;3:227
  1. J. S. Malpas,
  2. Ronald Bodley Scott

    Abstract

    In a preliminary study rubidomycin was found capable of inducing remission in adults with acute leukaemia, the remission rate in acute myeloblastic leukaemia comparing favourably with that achieved with previous forms of therapy. Marrow aplasia and cardio-toxicity occurred in a number of patients. Supportive measures during the former and early recognition by frequent electrocardiography can do much to mitigate these toxic effects.

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