Papers And Originals

Oxytocinase in Plasma and Placenta in Normal and Prolonged Labour

Br Med J 1968; 3 doi: https://doi.org/10.1136/bmj.3.5610.96 (Published 13 July 1968) Cite this as: Br Med J 1968;3:96
  1. V. S. Mathur,
  2. J. M. Walker

    Abstract

    In prolonged labour (dystocia) the level of activity of the enzyme oxytocinase is increased in the plasma and decreased in the placenta; the ratio of its activity in the placenta to that in plasma is less than half that found in normal labour. A possible explanation is that oxytocinase is derived mainly from the placenta and that during prolonged labour the enzyme escapes into the maternal blood stream.