Research Article

Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses.

Br Med J (Clin Res Ed) 1987; 294 doi: https://doi.org/10.1136/bmj.294.6579.1051 (Published 25 April 1987) Cite this as: Br Med J (Clin Res Ed) 1987;294:1051
  1. P W Soothill,
  2. K H Nicolaides,
  3. S Campbell

    Abstract

    The umbilical venous oxygen and carbon dioxide tensions, pH, lactate and glucose concentrations, nucleated red cell (erythroblast) count, and haemoglobin concentration were measured in 38 cases of intrauterine growth retardation in which fetal blood sampling was performed by cordocentesis. The oxygen tension was below the normal mean for gestational age in 33 cases; in 14 it was below the lower limit of the 95% confidence interval for normal pregnancies. The severity of fetal hypoxia correlated significantly with fetal hypercapnia, acidosis, hyperlacticaemia, hypoglycaemia, and erythroblastosis. These findings indicate that "birth asphyxia" is not necessarily due to the process of birth.