Research Article

Selective consumption of large platelets during massive bleeding.

Br Med J (Clin Res Ed) 1985; 291 doi: http://dx.doi.org/10.1136/bmj.291.6488.95 (Published 13 July 1985) Cite this as: Br Med J (Clin Res Ed) 1985;291:95
  1. C B Thompson

    Abstract

    To see whether selective consumption of either small or large platelets occurs during haemostasis in vivo the mean platelet volume was studied in six patients who developed thrombocytopenia after trauma. The mean platelet volume at the onset of thrombocytopenia was significantly lower than that on admission (p less than 0.01): selective loss of large platelets had occurred.