Research Article

Fetal haematology in rhesus isoimmunisation.

Br Med J (Clin Res Ed) 1985; 290 doi: (Published 02 March 1985) Cite this as: Br Med J (Clin Res Ed) 1985;290:661
  1. K H Nicolaides,
  2. C H Rodeck,
  3. D S Millar,
  4. R S Mibashan


    Haematological studies were carried out in pure fetal blood samples obtained fetoscopically in 29 rhesus isoimmunised pregnancies at 18-24 weeks' gestation, and the values were compared with those obtained in 62 normal control pregnancies. Fetal reticulocytosis or erythroblastaemia was seen only in association with a haemoglobin concentration of 4 g/dl or less. Ten of the 14 fetuses with a haemoglobin concentration below 4 g/dl showed ultrasonographic evidence of hydrops.