Research Article

Anaphylactic reaction to aprotinin despite negative ocular sensitivity tests.

Br Med J (Clin Res Ed) 1984; 289 doi: https://doi.org/10.1136/bmj.289.6453.1176 (Published 03 November 1984) Cite this as: Br Med J (Clin Res Ed) 1984;289:1176
  1. G A LaFerla,
  2. W R Murray

    Abstract

    A man with a history of pancreatitis was given aprotinin intravenously just before endoscopic retrograde pancreatography. Despite negative sensitivity tests with aprotinin eye drops he developed a profound anaphylactic reaction on intravenous administration of the drug. Ocular sensitivity tests may not predict severe anaphylactic reactions to intravenous aprotinin.